I have a small Gigabyte Core i7 mini-PC running HomeAssistant underneath Proxmox hypervisor so that it can support local text to speech and speech recognition with Assist. So not having any internal slots for the device I decided to give this external 4G LTE Industrial Mini PCIe to USB Adapter Enclosure a try, and it worked very well! Simply replace the SMA with RP-SMA to Fl cables that were included with my module (or you can buy them) and connect the Z-Wave and Zigbee antennas to the two ports. USB-C to the computer, I poked a USB hole through for the “USB Dual_Serial” to homeassistant and viola, HASS found the device on a VM reboot.
The only device I have set up so far is the U-TEC U-Bolt Pro Z-Wave Smart Lock and it was fairly easy to set up. It even was able to update the Z-Wave firmware in the deadbolt remotely!
I didn’t have to do anything manually I just plugged it in and HASS worked. I followed directions for the Raspberry Pi with HASS which are identical since I am using a USB port.